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Cirugía Plástica Ibero-Latinoamericana

versión On-line ISSN 1989-2055versión impresa ISSN 0376-7892


PELLON, Marco Aurelio. Molecular and microanatomic characteristics of fat and its application in the treatment of acute burns and sequelae. Cir. plást. iberolatinoam. [online]. 2020, vol.46, suppl.1, pp.53-62.  Epub 22-Jun-2020. ISSN 1989-2055.

Background and objective

During the past 20 years, adipose tissue has been universally recognized as more than just an energy deposit and it is now known that fat is a tissue that has endocrine, paracrine and autocrine functions, capable of synthesizing and secreting several signaling cytokines called adipokines, in addition to hormones, pro hormones, enzymes and genetic material.

This article aims to analyze molecular biology, microanatomy, intercellular communication and the regenerative potential of adipose tissue, presenting the author’s experience in the use of fat to treat lesions caused by burns in various phases, depths and anatomical regions.


Study conducted in several patients who suffered thermal, electrical and chemical burns, both acute and late, treated in a Burn Treatment Unit. Topical application and fat injection techniques are addressed, depending on the types of burns or sequelae.


The results obtained with this technique in several cases of short- and long-term burns are presented, demonstrating the effectiveness of this new modality of treatment.


Preservation of the metabolic activity of the aspirated adipose tissue is very important to achieve the expected regenerative result.

Palabras clave : Burns; Fat; Burn sequels.

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