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Oncología (Barcelona)

versão impressa ISSN 0378-4835


RIVERA BAUTISTA, J. A. et al. Gastric plasmacytoma-like in a patient with heart transplant: Review of some etiopathogenic and therapeutic concepts. Oncología (Barc.) [online]. 2006, vol.29, n.7, pp.41-46. ISSN 0378-4835.

Plasmacytoma-like tumour is an infrequent entity observed among the post-transplant lymphoproliferative disorders (PTLD). Immunosuppression and Epstein.Barr virus (EBV) infection play an important role in the development of the process. The preoperative diagnosis is difficult, but it can be made by means of immunohistochemical studies of the biopsies. The adequate treatment consists of surgery, radiotherapy and reduction of the administered immunosuppressor drugs. The patients need a close follow up because the resulting immusuppression facilitates the recurrence of the tumour or the rejection of the transplanted organ. We present the case of a patient with a heart transplant who developed a gastric plasmacytoma-like PTLD seven years after transplantation. We discuss the etiopathogenic theories, the diagnostic criteria and the treatment options.

Palavras-chave : Plamacytoma-like neoplam; Post-transplant lymphoproliferative disorder (PTLD); Epstein-Barr virus (EBV); Immunosuppression.

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