Abstract

CUENCA, F. et al. Experience with granulocytapheresis in Crohn's disease. Rev. esp. enferm. dig. [online]. 2004, vol.96, n.7, pp.501-506. ISSN 1130-0108.

Objective: to describe our experience with granulocyte apheresis to induce remission in patients with active Crohn's disease refractory to conventional treatment. We summarize the results previously obtained with this technique. Conclusions: granulocyte apheresis is a safe and well tolerated therapeutic modality that can be a valid therapeutic alternative in the induction of remission in inflammatory bowel disease, although controlled clinical trials must be conducted to define long-term efficacy, as well as to establish “optimal patient” selection, re-treatment interval, and number of sessions.

Keywords : Granulocyte apheresis; Leukocyte apheresis; Ulcerative colitis; Crohn's disease; Inflammatory bowel disease.

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