Revista Española de Enfermedades Digestivas
versión impresa ISSN 1130-0108
CHEN, S. Y. et al. Recurrence of hepatocellular carcinoma after liver transplantation presenting as anastomotic biliary stricture. Rev. esp. enferm. dig. [online]. 2008, vol.100, n.7, pp.434-436. ISSN 1130-0108.
A 52-year-old man visited our hospital complaining of anorexia and fatigue two months after receiving orthotopic liver transplantation for hepatocellular carcinoma. A laboratory investigation demonstrated a clinical picture of obstructive jaundice. T-tube cholangiography showed biliary stricture over the anastomotic site. Percutaneous transluminal balloon dilatation and stenting was attempted but failed. Magnetic resonance cholangiography showed possible tumor recurrence over the site of the anastomotic biliary stricture. A biopsy sample was obtained via ultrasound-guided aspiration and histopathological study revealed inflammatory and fibrotic changes. With high suspicion of recurrence of the hepatocellular carcinoma, surgical exploration was performed and an intraoperative frozen section proved the recurrence. We thus diagnosed this case as a recurrence of hepatocellular carcinoma after liver transplantation. To our knowledge, there have been no previous reports of early tumor recurrence after liver transplantation being the cause of an anastomotic biliary stricture.
Palabras clave : Anastomotic biliary stricture; Orthotopic liver transplantation; Recurrence; Hepatocellular carcinoma.