Abstract

VAZQUEZ-MORON, Juan María et al. Crohn's-like disease in a patient with common variable immunodeficiency treated with azathioprine and adalimumab. Rev. esp. enferm. dig. [online]. 2013, vol.105, n.5, pp.299-302. ISSN 1130-0108.  https://dx.doi.org/10.4321/S1130-01082013000500010.

Common variable immunodeficiency (CVID) is the most frequent primary antibody deficiency. It is characterized by recurrent bacterial infections, and occurrence of autoimmune and neoplastic diseases is also frequent; there is also a high prevalence of gastrointestinal diseases. There are reports of inflammatory bowel disease in this entity, but incidence is low (2-4 %). We present the case of a patient with common variable immunodeficiency suffering a chronic diar-rhoea episode and who was diagnosed with ileocaecal Crohn's-like disease after performing intestinal transit, CT abdomen and colonoscopy with biopsy. It was first treated with prednisone but on -showing cortisone dependency, treatment with azathioprine and adalimumab was started, with good results.

Keywords : Crohn's-like disease; Common variable immunodeficiency; Adalimumab; Azathioprine.

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