Abstract

GRAVITO-SOARES, Marta et al. Fecal microbiota transplantation in recurrent Clostridium difficile infection in a patient with concomitant inflammatory bowel disease. Rev. esp. enferm. dig. [online]. 2017, vol.109, n.6, pp.473-476. ISSN 1130-0108.  https://dx.doi.org/10.17235/reed.2017.4819/2016.

The use of fecal microbiota transplantation in recurrent Clostridium difficile infection and coexistent inflammatory bowel disease remains unclear. A 61-year-old man with ulcerative pancolitis was diagnosed with a third recurrence of Clostridium difficile infection, previously treated with metronidazole, vancomycin and fidaxomicin. Fecal microbiota transplantation of an unrelated healthy donor was performed by the lower route. After a twelve month follow-up, the patient remains asymptomatic without Clostridium difficile infection relapses or inflammatory bowel disease flare-ups. Fecal microbiota transplantation is relatively simple to perform, well-tolerated, safe and effective in recurrent Clostridium difficile infection with ulcerative pancolitis, as an alternative in case of antibiotic therapy failure.

Keywords : Recurrent Clostridium difficile infection; Ulcerative pancolitis; Fecal microbiota transplantation; Inflammatory bowel disease; Infectious colitis.

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