Mi SciELO
Servicios personalizadosServicios Personalizados
Revista
Articulo
Articulo en XML
Referencias del artículo
Traducción automática
Enviar articulo por emailIndicadores
Citado por SciELO 
Accesos
Links relacionados
Citado por Google 
Similares en
SciELO 
Similares en Google
Compartir
Permalink
Revista Española de Enfermedades Digestivas
versión impresa ISSN 1130-0108
Resumen
ROGER, Manuela et al. EUS-FNA cytological material from pancreatic lesions: the expression of cathepsins and its predictive value of malignancy. Rev. esp. enferm. dig. [online]. 2018, vol.110, n.7, pp.446-450. ISSN 1130-0108. https://dx.doi.org/10.17235/reed.2018.4200/2016.
Aims:
To assess the expression of cathepsins in pancreatic samples obtained by endoscopic ultrasonography and fine needle aspiration (EUS-FNA) and to investigate their relationship with the staging of the pancreatic ductal adenocarcinoma (PDAC).
Methods:
We prospectively included patients with solid pancreatic masses, in which EUS-FNA were performed. Cathepsins B, L, S and H expression was determined in FNA samples.
Results:
Seventeen FNA were performed. All cytological material was from PDAC. Expression of cathepsins was predominantly low (B 65%, L 23%, S 76%, and H 41%). We found no correlation between the expression levels and the extension of the neoplasm.
Conclusion:
Expression of cathepsins in the cytological material of PDAC is diverse but still poor to be useful in the pre-operative diagnosis. There is no correlation between the expression levels of cathepsins and the extension of the PDAC.
Palabras clave : Pancreatic neoplasms; Cathepsins; Endoscopic ultrasonography.
pdf
)
