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Revista Española de Enfermedades Digestivas

versión impresa ISSN 1130-0108

Resumen

MARIN-GABRIEL, José-C. et al. Switching from endoscopic submucosal dissection to salvage piecemeal knife-assisted snare resection to remove a lesion: a preoperative risk score from the beginning. Rev. esp. enferm. dig. [online]. 2018, vol.110, n.11, pp.699-705. ISSN 1130-0108.  http://dx.doi.org/10.17235/reed.2018.5608/2018.

Background and aims:

endoscopic submucosal dissection (ESD) in the Western setting remains a challenge. Therefore, other simplified techniques such as knife-assisted snare resection (KAR) have been reported to overcome this issue.

Methods:

patients who underwent an ESD for the treatment of gastrointestinal neoplasms were included in a retrospective cross-sectional observational study. Factors associated with the end of ESD as a salvage p-KAR were identified and a logistic regression model was developed.

Results:

a total of 136 lesions in 133 patients were analyzed. Operator experience of under 50 cases and the combination of lesion size > 30 mm and colorectal location were independent predictive factors for switching to a salvage p-KAR according to the multivariate logistic regression analysis. We developed a risk scoring system based on these four variables (experience, size, location and the combination of size and location) with a receiver operating characteristic curve of 0.81 (95% CI: 0.74-0.89). The diagnostic accuracy of the score for a cut-off point ≥ 5 had a sensitivity of 0.79 (95% CI: 0.66-0.93) and a specificity of 0.71 (95% CI: 0.61-0.80).

Conclusion:

a simple predictive score system that includes four preoperative factors accurately predicts ESD to finish as a p-KAR. A careful selection of cases considering these variables could be useful to achieve better outcomes in the Western setting.

Palabras clave : Endoscopic submucosal dissection; Endoscopic mucosal resection; Predictive value; Sensitivity and specificity; ROC curve; Area under curve.

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