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Revista Española de Cirugía Oral y Maxilofacial

versión impresa ISSN 1130-0558


ARIAS GALLO, J. et al. The use of lyophilized bovine collagen (Colloss®) for treating mandibular cysts: Description of a clinical series. Rev Esp Cirug Oral y Maxilofac [online]. 2007, vol.29, n.4, pp.270-278. ISSN 1130-0558.

The treatment of mandible bone cysts commonly leads to the development of bone defects. When the defects are less than 3 cm and located away from the alveolar ridge, they usually heal spontaneously within a 6 to 12 month period. However, if the defect is larger, the regenerative ability of the body is overcome. Colloss® appears to be an interesting osteoinductive biomaterial. It is a lyophilized complex from extracellular matrix proteins of bovine bone. It is composed primarily of type I collagen and variable amounts of BMPs. Between February 2002 and January 2004, 7 patients with mandible cysts were treated with lyophilized collagen to enhance bone regeneration. In some of the cases this was combined with autologous bone or a titanium mesh. We observed incompatibility with autologous bone and a slight tendency for intraoral exposure of the titanium mesh. Apart from this, we noted adequate bone healing and regeneration in all the cases. For the authors of this paper, the advantages of lyophilized collagen are the following: osteoinductive capacity, absence of any major adverse effects and the role played in the early detection of recurrence. Its possible disadvantages are its difficult handling and the inherent complications related to bovine xenografts.

Palabras clave : Colloss®; Mandible bone cyst; Lyophilized collagen; bone regeneration.

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