Abstract

BARRIENTOS LEZCANO, F.J. et al. Bisphosphonate induced osteonecrosis of the jaws: prevention and therapeutic approach. Rev Esp Cirug Oral y Maxilofac [online]. 2007, vol.29, n.5, pp.309-317. ISSN 2173-9161.

Introduction. Bisphosphonate-induced osteonecrosis of the jaws might reach epidemic proportions due to the widespread use of this therapy. Materials and methods. A protocol for prevention and treatment of this pathology is shown. Three clinical cases are reported. Results. It is quite difficult to reach restitutio ad integrum, but stopping the progress of the disease is possible. Discussion. Surgical treatment and cessation of bisphosphonate therapy are of no use. Only antibiotics and oral chlorhexidine have shown some benefits. Conclusions. An accurate preventive attitude is mandatory prior to undergoing bisphosphonate therapy. If osteonecrosis of the jaws is present, management should be conservative.

Keywords : Osteonecrosis; Bisphosphonates; Avascular necrosis; Jaws; Mandible.

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