SciELO - Scientific Electronic Library Online

vol.21 número3 índice de autoresíndice de materiabúsqueda de artículos
Home Pagelista alfabética de revistas  

Servicios Personalizados



Links relacionados

  • En proceso de indezaciónCitado por Google
  • No hay articulos similaresSimilares en SciELO
  • En proceso de indezaciónSimilares en Google



versión impresa ISSN 1130-1473


OTERO-RODRIGUEZ, A.; SARABIA-HERRERO, R.; GARCIA-TEJEIRO, M.  y  ZAMORA-MARTINEZ, T.. Spontaneous malignant transformation of a supratentorial pilocytic astrocytoma. Neurocirugía [online]. 2010, vol.21, n.3, pp.245-252. ISSN 1130-1473.

Pilocytic astrocytoma (PA) is a circumscribed neoplasia considered as a grade I astrocytoma by the World Health Organization. Its most common location is the cerebellum and it develops during the first two decades of the life. Prognosis is mostly excellent if gross-total resection can be achieved, with 10-year survival rates of up to 80%. Anaplastic or malignant transformation (MT) can rarely occur and is usually related to previous radiation. Spontaneous MT has exceptionally been reported. Histological criteria for diagnosis of MT are unclear, so no consensus exists. We present an atypical case of MT of a frontal PA without previous radiotherapy in a 28 years old patient. Also, we review the literature about prognostic factors of PA and discuss histological features that are considered as anaplastic or malignant in the PA.

Palabras clave : Pilocytic astrocytoma; Malignant transformation; Radiotherapy; Prognosis.

        · resumen en Español     · texto en Inglés     · Inglés ( pdf )