Revista de la Sociedad Española del Dolor
versión impresa ISSN 1134-8046
ALONSO, A. y FRANCO, Mª L.. Diferences in the measurements of quality of lire trough Coop-Wonca cartoons in fibromyalgia patients in treatment with or without pregabaline. Rev. Soc. Esp. Dolor [online]. 2006, vol.13, n.1, pp.18-23. ISSN 1134-8046.
Objective: About the evolution of patients with Fibromyalgia it is interesting to know the results of measures assesing of the health-related quality of life.The interest annhace with the use of a new drug, pregabalin, the lastest generation anti-convulsivant, a ligand of a2-d subunit of calcium chanels. Helped by the COOP-WONCA charts ( reliable Spanish version of Nottingham Health Profile) our aim is determine if pregabalin improve the health-related quality of life in a group of Fibromyalgia affected patients. Methods: This trial compared the results of Coop-Wonca charts without pregabalin, with dosis of 300 and 600 mg/day pregabalin in a group of 16 patients with Fibromyalgia. All patients were continuated with their medications. Results: Pregabalin at 300 and 600 mg/day did not significantly improvement in the results of Coop/Wonca charts (p 0.05). Dizziness and weight gain were the most frequent adverse events. Conclusion: The scale of health-related quality of life Coop/Wonca did not result in improvement in our group of 16 patientes with Fibromyalgia when pregabalin was add to the treatment. Further study with a large group of patients is necessary to draw more conclusions on this point.
Palabras clave : Health-related quality of life; Fibromyalgia; Pregabalin; Coop-Wonca charts.