SciELO - Scientific Electronic Library Online

vol.93Design and validation of a questionnaire on the attitudes of health professionals towards the official recommendation of influenza vaccinationWilson disease: the look of medical staff, patients and family members author indexsubject indexarticles search
Home Pagealphabetic serial listing  

Services on Demand




Related links

  • On index processCited by Google
  • Have no similar articlesSimilars in SciELO
  • On index processSimilars in Google


Revista Española de Salud Pública

On-line version ISSN 2173-9110Print version ISSN 1135-5727


HERNANDEZ-GARCIA, Ignacio; CHAURE-PARDOS, Armando; AIBAR-REMON, Carlos  and  GRUPO TRABAJO VACUNAS HCULB. Assessment of the effectiveness of an intervention to improve immunization coverage in splenectomy patients. Rev. Esp. Salud Publica [online]. 2019, vol.93, e201904019.  Epub Sep 07, 2020. ISSN 2173-9110.


Splenectomized patients have an increased risk of sepsis caused by encapsulated bacteria. Pneumococcal, meningococcal and Haemophilus influenzae B vaccination is recommended in this group. The aim of our study was to assess the impact of the introduction of an immunization hospital clinic on their immunization coverages.


Quasi-experimental study. The control group included patients splenectomized between January 2012-April 2014, and the intervention group included patients splenectomized between May 2014-December 2016. The global and specific immunization coverages were compared between both groups using a Chi-square test.


80 patients were analyzed. The most commonly administered vaccine was the 23-valent pneumococcal polysaccharide vaccine (65%). A significant improvement was observed both in the global immunization rate (17.1% in the pre-intervention study vs. 57.8% in the post-intervention study) (RR: 3.37; 95% CI: 1.56-7.27) and in the specific immunization rate for the Haemophilus influenzae B, meningococcal C and 13-valent pneumococcal conjugate vaccines.


Introducing an immunization hospital clinic is an effective measure to improve the immunization coverage of splenectomy patients.

Keywords : Vaccination Coverage; Splenectomy; Preventive medicine; Outpatient clinics; Risk Groups.

        · abstract in Spanish     · text in Spanish     · Spanish ( pdf )