Abstract

SANTOS, V.M. et al. Infiltrating gastric adenocarcinoma with disseminated osteoblastic metastases. Anales Sis San Navarra [online]. 2013, vol.36, n.1, pp.153-157. ISSN 1137-6627.  https://dx.doi.org/10.4321/S1137-66272013000100022.

We report the case of a man with a diagnosis of invasive gastric adenocarcinoma associated with scattered osteoblastic metastases. This 65-year-old patient was admitted with nausea, vomiting and abdominal pain, in addition to loss of weight (13 Kg in 3 months). Upper digestive endoscopy revealed extensive infiltrating changes in the body of the stomach, and histopathologic data confirmed the diagnosis of a Borrmann IV gastric adenocarcinoma. Complementary exams were indicative of a gastric cancer with bone metastases, characterized by disseminated osteoblastic images of the scintigraphy of the skeleton. Palliative chemotherapy was the treatment of first choice. High serum levels of CA 19-9, CEA and alkaline phosphatase can constitute useful indicative tools of this challenging condition. Images from a scintigraphy study of the skeleton can characterize the type and extension of bone metastases. The aim of this case study is to report a case of a very uncommon condition, considering that disseminated osteoblastic metastases rarely develop in this kind of tumor.

Keywords : Adenocarcinoma; Bone metastasis; Gastric tumor.

        · abstract in Spanish     · text in English     · English ( pdf )