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ARTEAGOITIA CALVO, María Iciar et al. Systemic antibiotherapy in the prevention of dry socket in lower third molar exodontia: systematic review. RCOE [online]. 2002, vol.7, n.6, pp.603-611. ISSN 1138-123X.

Introduction: The objective of this systematic review is to provide an answer to the question: Is the frequency of dry socket in lower third molar surgery reduced with efficacy using systemic antibiotics?. Method: Unlimited bibliographic search in repertories and computer databases. Inclusion criteria: exposure (systemic antibiotherapy), effect (dry socket) and design (randomised clinical trials -evidence I-). Validity of the preliminary studies was assessed according to the synthesis of the best available evidence (Jadad scale) and individual components. From the trials chosen, the external validity of their conclusions was verified. Results: Eleven clinical trials complied with the inclusion criteria obtaining = 1 points on the Jadad scale. Intention to treat analysis was not performed on any of the studies. Power analysis and preliminary calculation of the sample size was performed on only one, whereas the confidence interval was performed on two. Conclusion: There is no evidence for or against the efficacy of systemic preventive antibiotherapy in lower third molar exodontia.

Keywords : Systematic review; third molar; exodontia; antibiotics; dry socket.

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