SciELO - Scientific Electronic Library Online

vol.19 issue3Emotional well-being amongst female inmates in prisons: the relevance of their addictive history and their country of originCongenital syphilis in 2 children in a Bolivian prison author indexsubject indexarticles search
Home Pagealphabetic serial listing  

Services on Demand




Related links

  • On index processCited by Google
  • Have no similar articlesSimilars in SciELO
  • On index processSimilars in Google


Revista Española de Sanidad Penitenciaria

On-line version ISSN 2013-6463Print version ISSN 1575-0620


FLORES-CHAVEZ, A.; CARRION, J.A.; FORNS, X.  and  RAMOS-CASALS, M.. Extrahepatic manifestations associated with Chronic Hepatitis C Virus Infection. Rev. esp. sanid. penit. [online]. 2017, vol.19, n.3, pp.87-97. ISSN 2013-6463.

Chronic hepatitis C virus (HCV) infection has been associated with both organ-specific and systemic autoimmune diseases, with cryoglobulinemia being the most frequent associated disease. Experimental, virologic, and clinical evidence have demon-strated a close association between HCV infection and some systemic autoimmune diseases, especially Sjögren’s syndrome, but also rheumatoid arthritis and lupus. A higher prevalence of hematological processes has also been described in patients with HCV infection, including cytopenias and lymphoproliferative disorders (B-cell lymphoma). In addition, patients with chronic HCV infection have a higher frequency of other extrahepatic manifestations including endocrine, metabolic and cardiovascular disorders that may worse the prognosis of patients, along with neuropsychiatric manifestations and general symptoms that have a significant influence on the quality of life of the patient. Direct-acting antiviral therapies (DAAs) that have recently begun to be used are providing the opportunity to effectively cure chronic HCV infection and reduce the burden of both hepatic and extrahepatic complications.

Keywords : prisons; hepacivirus; hepatitis C; antiviral agents; autoinmune diseases; lymphoma; Spain; diabetes mellitus.

        · abstract in Spanish     · text in English     · English ( pdf ) | Spanish ( pdf )