SciELO - Scientific Electronic Library Online

vol.11 número5Spindle cell lipoma of the floor of the mouth: A case report índice de autoresíndice de materiabúsqueda de artículos
Home Pagelista alfabética de revistas  

Servicios Personalizados




Links relacionados

  • En proceso de indezaciónCitado por Google
  • No hay articulos similaresSimilares en SciELO
  • En proceso de indezaciónSimilares en Google


Medicina Oral, Patología Oral y Cirugía Bucal (Internet)

versión On-line ISSN 1698-6946


PONTE FERNANDEZ, Nerea; ESTEFANIA FRESCO, Ruth  y  AGUIRRE URIZAR, José Manuel. Bisphosphonates and Oral Pathology I: General and preventive aspects. Med. oral patol. oral cir.bucal (Internet) [online]. 2006, vol.11, n.5, pp.396-400. ISSN 1698-6946.

Bisphosphonates constitute a group of drugs capable of modulating bone turnover, and reduce its remodelling when an excessive resorption occurs. This is why they are indicated in a large group of bone diseases like postmenopausal osteoporosis or osteolisis associated with breast cancer or multiple myeloma. Over the last years and due to their extensive use, many cases of complications associated with their use have been published. Among the most important possible adeverse effects are the oral ones, with the appearance of ulcerations and, especially, osteonecrosis of the jaws associated with this therapy. In this paper, we have analyzed the general characteristics of these drugs and their mechanisms of action as well as the described adverse effects, especially oral and maxillofacial has been made special reference regarding the prevention of osteonecrosis of the jaws, hightened by cases described in medical and odontological literature. The preventive protocol backs up the fundamental role of the odontologist in the effective prevention of this process before, during and after the treatment.

Palabras clave : Bisphosphonates; adverse effects; osteonecrosis; jaws; prevention.

        · resumen en Español     · texto en Español | Inglés     · Español ( pdf ) | Inglés ( pdf )


Creative Commons License Todo el contenido de esta revista, excepto dónde está identificado, está bajo una Licencia Creative Commons