Avances en Periodoncia e Implantología Oral
versión impresa ISSN 1699-6585
Advance malignant melanoma is generated from proliferating dendritic (nevic) cell progenitors. They are important on the histogenesis and risk of tumor development. From 30% to 37% from high air-digestic track melanoms, there are associated with premalignant cell dendritic lesions. Histophatological approaches agree in consider size of tumor, atypical cells, distribution of this cells and borders of lesion as valued markers. Major advances in tumor irnmunology, have led to understand tumor cell-T cell interactions. A number of melanom associated antigens have been identified and molecularly characterized.
Palabras clave : Melanoma; Nevus; Precocious Diagnosis; Inmunology; Angiogenesis; Metastasis.