Abstract

ARDILA MEDINA, C.M.  and  LAFAURIE VILLAMIL, G.I.. Association between porphyromonas gingivalis and C-reactive protein in systemic inflammatory diseases. Avances en Periodoncia [online]. 2010, vol.22, n.1, pp.45-53. ISSN 2340-3209.

C-reactive protein (CRP) is a serological marker of systemic inflammation that has been associated with increased risk systemic inflammatory diseases. Periodontitis has also been linked to elevated CRP levels in adults as well as with a reduction in PCR after its treatment. It is thus postulated that CRP might be a possible mediator of the association between periodontitis and systemic inflammatory diseases. Periodontal pathogens do not induce only local inflammation and tissue destruction. They are also involved in systemic increases in inflammatory and inmmune responses. Several studies have investigated antibodies to various periodontal pathogens in relation to CRP, but the association has been reported consistently only for IgG to Porphyromonas gingivalis. Evidence is sparse on the association between a direct measure of periodontal pathogens and CRP, while it is more important because the presence of antibody titers is not necessarily indicative of an active infection.

Keywords : C-reactive protein; inflammation; periodontitis; porphyromonas gingivalis.

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