Avances en Periodoncia e Implantología Oral
Print version ISSN 1699-6585
ARDILA MEDINA, C.M.. Resolvin E1 promotes resolution of inflammation in periodontal disease. Avances en Periodoncia [online]. 2012, vol.24, n.2, pp.71-75. ISSN 1699-6585.
Periodontal diseases are inflammatory processes in which microbial etiologic factors induce a series of host responses that mediate an inflammatory cascade of events in an attempt to protect and heal the periodontal tissues. Beside to the signals that initiate the inflammatory events, periodontal tissues are capable of generating or stop signals that control the inflammation. In addition to the traditional pro- and anti-inflammatory mechanisms, novel endogenous lipid mediators could represent a pro-resolution phase. Pro-resolution has a big advantage over the traditional methods in that it suppresses excessive cellular activity. A new treatment concept where natural pathways of resolution of inflammation can be used to limit inflammation and promote healing and regeneration with minor risk of side-effects.
Keywords : Resolvin E1; Anti-inflammatory; Periodontal disease.