Abstract

CARBAYO GARCIA, José Juan et al. Assessment of the kidney function in type 2 diabetic patients and their appropriateness for oral antidiabetic treatment. Rev Clin Med Fam [online]. 2014, vol.7, n.1, pp.8-13. ISSN 2386-8201.  https://dx.doi.org/10.4321/S1699-695X2014000100002.

Objective: Assessment of the kidney function by glomerular filtrate rate (GFR) in type 2 diabetic subjects and their appropriateness for antidiabetic oral treatment. Materials and Method: Cross-sectional observational study carried out in a sample of type 2 diabetic subjects aged between 18 and 75 years old treated with oral antidiabetic drugs (OADs) in the Health area of Talavera de la Reina (Toledo, Spain) in the period from November 2011 to June 2012. Results: A group of 191 pacients was studied: 103 men and 88 women, with an average age of 62.5 (8.3) years. The FGR was calculated in 168 patients (87.96%), obtaining an FGR average value of 95.5 (25.1). Seven patients (3.7%) were within the 45-60 range and one (0.5%) with FGR under 30. The prevalence of chronic kidney disease (CKD) was 4.8% [CI95% 2, 4-9,1]. The most widely used drug was metformine followed by IDPP4. In relation to GFR in the 45-60 range, the most frequent drugs were DPP4 inhibitors alone or combined with metformine; in the patient with FGR below 30, the drug used was metformine. Conclusions: The prevalence found was lower than that in other previous studies published. The estimation of FGR is important in diabetic patients. In our group of patients, the treatment guidelines are generally adjusted to the kidney function.

Keywords : Chronic kidney disease; Diabetes mellitus; Glomerular filtration; Oral antidiabetic drugs; Primary health care.

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