SciELO - Scientific Electronic Library Online

vol.9 issue1Foodborne outbreak of norovirus: epidemiologycal study and Health measures implemented to prevent recurrenceUsefulness of clinical prediction criteria and rapid antigen detection testing for the management of acute pharyngitis in an emergency department author indexsubject indexarticles search
Home Pagealphabetic serial listing  

Services on Demand




Related links

  • On index processCited by Google
  • Have no similar articlesSimilars in SciELO
  • On index processSimilars in Google


Revista Clínica de Medicina de Familia

On-line version ISSN 2386-8201Print version ISSN 1699-695X


DIAZ GRAVALOS, Gabriel J. et al. Relationship between prostate-specific antigen testing and androgen deprivation therapy use: an ecological study. Rev Clin Med Fam [online]. 2016, vol.9, n.1, pp.16-22. ISSN 2386-8201.

Objective: To determine if a larger number of determinations of prostate-specific antigen (PSAn) is associated with an increased number of androgen deprivation therapies (ADTn). Study Design: Transversal ecological study. Setting: Primary care at provincial level. Participants: Permanent general practitioners with at least 1-year tenure. Main measurements: The number of men over 50 (V50) and their age, PSAn and ADTn in 2012 were determined for each family medicine quota in the region of Ourense (Spain). A sample size of 113 physicians was calculated. The association between ADTn and PSAn was analyzed by Spearman correlation. The ADTn was considered as a dependent variable in a multiple linear regression analysis, including as covariates gender of the physician, rural or urban context of work, V50, patient age and PSAn. A p value <0.05 was considered significant. Results: We studied 265 physicians, 54.1% men. V50 average was 272.6 (SD: 68.6), ADTn was 8.5 (4.0) per medical quota, and PSAn was 90.9 (52.4)/year. There was a relationship between the number of V50 and PSAn (Spearman's Rho=0,4; CI95%:0.3-0.7; p=0.01) and between ADTn and age of V50 (Spearman's Rho=0.2; CI95%:0.04-0.31; p<0.001). Association was found between ADTn and PSAn (Spearman's Rho=0.2; CI95%:0.04-0.31; p=0.01) and number of V50 and ADTn (Spearman's Rho=0,5; CI95%: 0,75-0,84; p < 0,001) . Linear regression showed a relationship between ADTn and age of males (p <0.001) and number of V50 (p <0.001). Conclusions: A higher frequency of PSA testing does not follow from an increased diagnosis of PCa measured by the number of ADT, that is associated with the age and number of males over 50.

Keywords : Prostatic Neoplasms; Prostate-Specific Antigen; Screening; Efficiency; Androgen Antagonists.

        · abstract in Spanish     · text in Spanish     · Spanish ( pdf )


Creative Commons License All the contents of this journal, except where otherwise noted, is licensed under a Creative Commons Attribution License