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Revista Clínica de Medicina de Familia

On-line version ISSN 2386-8201Print version ISSN 1699-695X


SANCHEZ LLANOS, Pedro  and  SANCHEZ HERNANDEZ, Cristina. Osteopoikilosis. Rev Clin Med Fam [online]. 2017, vol.10, n.2, pp.145-149. ISSN 2386-8201.

Osteopoikilosis is an uncommon osteosclerotic dysplasia. It is a rare and benign autosomal dominant genetic disorder, characterized by a symmetric but unequal distribution of multiple hyperostotic areas in different parts of the skeleton. It is usually an asymptomatic bone disease that develops during childhood and persists throughout life. There is no exact evidence of its etiology and pathogenesis. Diagnosis is made incidentally from radiographs, which show multiple small, well defined, variably shaped and widely distributed sclerotic areas over the skeleton. It may be confused with other conditions, such as osteoblastic metastases. So, osteopoikilosis must be present in differential diagnosis when bone lesions are identified on plain radiographs to avoid alarming the patient with more serious diseases and misdiagnosis.

Keywords : Osteopoikilosis; Buschke-Ollendorf Syndrome; Osteopathia Condensans Disseminata.

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