Abstract

GOMEZ FERNANDEZ, Esperanza  and  ZUFIA GARCIA, Francisco Javier. Lymphatic filariasis. Rev Clin Med Fam [online]. 2020, vol.13, n.1, pp.89-92.  Epub Apr 20, 2020. ISSN 2386-8201.

Lymphatic filariasis is a group of diseases caused by nematodes of the family Filarioidea which require vectors for their transmission. The number of people infected globally is estimated at 120 million, two thirds of which are in Asia. The clinical manifestations of this disease are varied (asthenia, fever, lymphedema, etc.) and will depend on the presence of adult worms in lymph vessels, on the immune response of the host, and on the endosymbiotic response to Wolbachia bacteria. Diagnosis is confirmed by detection and visualization of microfilariae in blood or skin. Drug treatment is mainly based on the use of diethylcarbamazine. Doxycycline is also recommended in species in which the presence of Wolbachia endosymbiotic bacteria has been proven.

Keywords : Filariasis, Lymphatic; Wolbachia; Nematoda; Antinematodal Agents.

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