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Sanidad Militar

versión impresa ISSN 1887-8571

Resumen

MARQUES NEGREDO, M.ªL. et al. Medical identification: genetic fingerprint. Sanid. Mil. [online]. 2011, vol.67, n.3, pp.317-320. ISSN 1887-8571.  http://dx.doi.org/10.4321/S1887-85712011000400011.

Until recently the identification of human remains was based on comparing the data available of the missing persons before and after their disappearance or the disaster. Nowadays DNA analysis allows complete and reliable identification. The variability of the genome and the identification of that variability through the study of different polymorphisms (RFLP, SNP, etc) facilitate the differentiation of individuals with a high degree of reliability (99.999 %) and simultaneously follow their lineage. These techniques have been validated and are highly automated. The system "AmpFlSTR® Identifiler™ PCR Amplification Kit", together with the "ABI Prism® 3130 Genetic Analyzer" of Applied Biosystems, allows the identification of 15 loci and one sex marker (amelogenin). The CODIS system is integrated by 13 STR samong the 15 analyzed by this kit.

Palabras clave : DNA Spolymorphisms; STR; AmpFlSTR; Genetic fingerprint.

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