Abstract

ARANDA LOZANO, J. et al. Profitability of prostate biopsy and PSA values determination: impact of prostate cancer and post-biopsy complications. Sanid. Mil. [online]. 2016, vol.72, n.4, pp.260-265. ISSN 1887-8571.

Aim: To determinate the diagnosis rate of prostate cancer (CaP) of our hospital through prostate biopsy (Pb) and to analyse whether there are significant differences between the diverse variables of PSA and the anatomic-pathology results. In addition an to a lesser extent, to study our rates of post-biopsy complications. Material and Methodology: retrospective research, both descriptive and analytical, of the patients who underwent biopsy in 2014, analysing the quantitative values of age, free PSA, total PSA, free/ total PSA quotient and number of cylinders, and analysis of the qualitative variables resulting from anatomic-pathology and further complications. Results: The research includes 86 patients of 67.5 years old average [49-84]. The average total PSA was 7,67 ng/dl [2,83-29, free PSA 1,05 ng/dl [0,32-2,45] and PSA quotient of 0,16 [0,05-0,31]. The average cylinders obtained with Pb was 10.5 cylinders [4-18]. The rate of positive results in Bp was 30.2% (26 patients). When comparing patients with positive and negative Pbs, significant differences were found between free PSA values (p=0,039) and those of PSA quotient (p=0,015). Four patients required hospitalisation after Pb due to unforeseen complications. Conclusions: Our diagnosis rate of CaP through Pb is similar to the one of other described series. The PSA free/ total quotient is a reliable tool to indicate a biopsy. Our rate of post-biopsy complications is similar to the ones described in European guidelines which implies our prophylaxis protocol for prostate biopsy is optimum.

Keywords : Prostate cancer; prostate biopsy; PSA; Prostatitis.

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