Abstract

PORTAL-NUNEZ, S.; DE LA FUENTE, M.; DIEZ, A.  and  ESBRIT, P.. Oxidative stress as a possible therapeutic target for osteoporosis associated with aging. Rev Osteoporos Metab Miner [online]. 2016, vol.8, n.4, pp.138-146. ISSN 2173-2345.

Senile or involutional osteoporosis is a major problem in the developed world. Recent studies point to increased oxidative stress associated with aging, whether biological or chronological, as an important factor in its development. In this review paper, we focus on bone tissue disorders related to aging, the source of oxidative stress and negative influence on bone tissue. Finally, we consider the potential oxidative stress therapies currently being developed for this disease.

Keywords : oxidative stress; osteoporosis; aging; fragility.

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