Abstract

AZNAR BARBERO, Sonia et al. Comparative study on patients treated with post-dilution on-line haemodiafiltration, different flow rates of dialysis fluid, real dialysis time and prescribed time. Enferm Nefrol [online]. 2013, vol.16, n.3, pp.155-160. ISSN 2255-3517.  https://dx.doi.org/10.4321/S2254-28842013000300003.

The dialysis dose (DD) is a key element of dialysis adequacy and affects survival of patients undergoing dialysis. Some elements standing out concerning the DD are: dialysis time, blood flow rate (Qb), transfer area coefficient (K₀A) and dialysate flow rate (Qd). The aim of this study is to find out whether Qd 800 ml / min and 240 minutes prescribed time is more effective than Qd 500 ml / min and 240 minutes prescribed time and also to compare Qd 500 ml/min and 240 minutes of real dialysis time. Patients and Methods A transversal prospective study was conducted of a population in dialysis, inclusion criteria being an adult treated with post-dilution on-line haemodiafiltration and sufficient blood flow rate. In all patients was performed 18 consecutive sessions varying Qd and time as follows: Stage 1: 6 sessions Qd 800 ml/min and prescribed time 240 minutes (F1) Stage 2: 6 sessions Qd 500 ml/min and prescribed time 240 minutes (F2) Stage 3: 6 sessions Qd 500 ml/min and real dialysis time 240 minutes (F3) Statistical analysis performed using SPSS 13.0 for Windows. Quantitative variables were expressed as mean, standard deviation and range, and qualitative variables expressed as frequency and percentage. Results 432 sessions analysed getting higher Kt and reinfusion volume (VTR) in stage 3 in relation to other stages. No significant difference between stage 1 and 2. Discussion and conclusions: No differences in dialysis efficacy Qd 500 ml / min versus Qd 800 ml / min. Nevertheless, increasing 10 minutes in each session, the dialysis dose increases 2.77 litres and VTR increases 9%, halving this way the number of patients that don´t reach 20 litres reinfusion volume. All this achieved with a lower fee due to the size difference bicarbonate concentrate packaging.

Keywords : Online haemodiafiltration; Dialysis fluid flow rate; KT; Dialysis dose; Time of dialysis.

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