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Enfermería Nefrológica

On-line version ISSN 2255-3517Print version ISSN 2254-2884


RUIZ GARCIA, Estíbaliz et al. Adherence in hemodialysis patients to the pharmacologic treatment. Enferm Nefrol [online]. 2016, vol.19, n.3, pp.232-241. ISSN 2255-3517.

Introduction: Poor long-term adherence to the treatment is recognized as one of the major clinical problems in the management of chronic diseases, in particular of advanced chronic kidney disease. Objective: To study the scientific production on the degree of adherence to the pharmacologic therapy in hemodialysis patients. Methods: A, no meta-analytic, systematic review was conducted through a search of the following databases: Scielo, PubMed and Google Scholar. Manuscripts in English and Spanish were included. Manuscripts dealing with treatment adherence in hemodialysis patients were analyzed. Results: We reviewed 19 articles, 6 reviews and 13 observational studies published between 2007 and 2015. Sociodemographic variables were studied: age, gender, socioeconomic status, marital status, race and employment status; clinical and psychosocial variables and factors related to medication. It was found that between 15-72% of patients on hemodialysis, have poor adherence to the pharmacologic treatment. Depression is associated with non-adherence. Age is associated with increased adherence. Conclusions: Patients on hemodialysis have often nonadherence to drug therapy, although with great variability due to differences in the definition and measurement of nonadherence. Depression seems to be the most influential predictor of non-adherence. Demographic and clinical factors are not consistently associated with non-adherence, except age, being older patients who have greater adherence.

Keywords : adherence to treatment; non-adherence; chronic diseases; renal patients; hemodialysis.

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