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Ars Pharmaceutica (Internet)

On-line version ISSN 2340-9894

Abstract

GOMEZ-DE RUEDA, Félix et al. First experiences of monitoring of vancomycin in a General Hospital of Specialties. Ars Pharm [online]. 2016, vol.57, n.4, pp.177-181. ISSN 2340-9894.  http://dx.doi.org/10.4321/S2340-98942016000400004.

Introduction: vancomycin is an effective antibiotic for the treatment of infections due to Gram-positive germs, however renal toxicity associated with its use, has relegated its use to use secondary lines. This fact has consolidated the empirical treatment with more expensive antibiotics. Objective: to analyze the data of monitoring of vancomycin and rating the efficiency facing the use of other antibiotics. Materials and methods: observational study where discusses monitoring pharmacokinetics of Vancomycin and a unit of pharmacokinetics clinical efficiency, with a population of 137 patients admitted to a general hospital specialties. Results: the use of Vancomycin in first intention meant a savings of € 16.472,82 regarding the use of € 83.039,83 the linezolid and daptomycin. However, 18% of our sample not could be treated with Vancomycin, making it necessary to have other drugs.

Keywords : vancomycin; monitoring; clinical pharmacokinetics.

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