SciELO - Scientific Electronic Library Online

vol.58 issue1Bibliometric analysis of Medication System Hospital author indexsubject indexarticles search
Home Pagealphabetic serial listing  

Services on Demand




Related links

  • On index processCited by Google
  • Have no similar articlesSimilars in SciELO
  • On index processSimilars in Google


Ars Pharmaceutica (Internet)

On-line version ISSN 2340-9894


MYKHAILENKO, Olga; KOVALYOV, Volodumur; KOVALYOV, Sergiy  and  KRECHUN, Anastasiia. Isoflavonoids from the rhizomes of Iris hungarica and antibacterial activity of the dry rhizomes extract. Ars Pharm [online]. 2017, vol.58, n.1, pp.39-45. ISSN 2340-9894.


The aim of the work was isolation and identification of the phenolic compounds from the rhizomes of Iris hungarica.

Materials and methods:

To establish by chemical and spectral methods for the structures of phenolic compounds, which were isolated from the rhizomes of Iris hungarica Waldst. et Kit. (Iridaceae family). Compounds were obtained by column chromatography on silica gel and their structures were determined by UV, IR, MS, 1H-NMR spectra methods. Preliminary screening of antibacterial activity was determined.


From the ethanolic extract of the rhizomes of I. hungarica, which is widespread in Ukraine, for the first time two new for this species isoflavones, tectorigenin and tectoridin and xanthone mangiferin, together with known isoflavonoids daidzein, genistein, formononetin were isolated. The dry extract of the rhizomes of I. hungarica at a concentration of 1% has shown the highest inhibitory activity for Gram-positive bacteria and fungi.

Keywords : isoflavonoids; tectorigenin; tectoridin; mangiferin; Iris hungarica; antibacterial activity.

        · abstract in Spanish     · text in English     · English ( pdf )