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Ars Pharmaceutica (Internet)

On-line version ISSN 2340-9894

Abstract

ROMERO-OTERO, Mónica et al. Leucocyte labelling with 99mTc-exametazime and polycythemia vera: a casual finding. Ars Pharm [online]. 2019, vol.60, n.4, pp.227-230.  Epub Mar 09, 2020. ISSN 2340-9894.  http://dx.doi.org/10.30827/ars.v60i4.9410.

The official World Health Organization classification of hematopoietic and lymphoid tissue tumors introduces in 2016 the concept of masked polycythemia vera (PV) and reveals that this entity has been underdiagnosed in the past. We present the case of a 49-year-old man, smoker, operated on for ankle fracture more than 15 years ago, referred to evaluate a possible associated infectious process. As there was no previous separation of the red blood cells by sedimentation during the leukocyte labelling procedure with 99mTc-exametazima, the causes of decreased erythrocyte sedimentation rate were reviewed. These include polyglobulia and smoking, both present in the patient. A haematological study was advised, which concluded with the diagnosis of PV. The indications of the specialist in Radiopharmacy allowed diagnosing a case not identified until then, although the patient had had symptoms for years.

Keywords : polycythemia vera; labelled leukocytes; erythrocyte sedimentation rate.

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