SciELO - Scientific Electronic Library Online

SciELO - Scientific Electronic Library Online

Referencias del artículo

BETANZOS-CABRERA, G.; ESTRADA-LUNA, D.; BELEFANT-MILLER, H.  y  CANCINO-DIAZ, J. C.. Mice fed with a high fat diet show a decrease in the expression of "toll like receptor" (TLR)2 and TLR6 mRNAs in adipose and hepatic tissues. Nutr. Hosp. [online]. 2012, vol.27, n.4, pp.1196-1203. ISSN 0212-1611.  http://dx.doi.org/10.3305/nh.2012.27.4.5842.

    1. Kawai T, Akira S. The roles of TLRs, RLRs and NLRs in pathogen recognition. Int Immunol 2009; 21 (4): 317-337. [ Links ]

    2. Akira S, Uematsu S, Takeuchi O. Pathogen recognition and innate immunity. Cell 2006; 124 (4): 783-801. [ Links ]

    3. Beutler B, Jiang Z, Georgel P, Crozat K, Croker B, Rutschmann S et al. Genetic analysis of host resistance: Toll like receptor signaling and immunity at large. Ann Rev Immunol 2006; 24:353-389. [ Links ]

    4. Iwasaki A, Medzhitov R. Toll-like receptor control of the adaptive immune responses. Nat Immunol 2004; 5 (10): 987-995. [ Links ]

    5. Wu XY, Gao JL, Ren MY. Expression profiles and function of Toll-like receptors in human corneal epithelia. Chin Med J 2007; 120 (10): 893-897. [ Links ]

    6. Rodríguez-Martínez S, Cancino-Díaz ME, Jiménez-Zamudio L, García-Latorre E, Cancino-Díaz JC. TLRs and NODs mRNA expression pattern in healthy mouse eye. Br J Ophthalmol 2005; 89 (7): 904-910. [ Links ]

    7. Otte JM, Rosenberg IM, Podolsky DK. Intestinal myofibroblasts in innate immune responses of the intestine. Gastroenterology 2003; 124 (7): 1866-1878. [ Links ]

    8. Baker BS, Ovigne JM, Powles AV, Corcoran S, Fry L. Normal keratinocytes express Toll-like receptors (TLRs) 1, 2 and 5: modulation of TLR expression in chronic plaque psoriasis. Br J Dermatol 2003; 148 (4): 670-679. [ Links ]

    9. Bsibsi M, Ravid R, Gveric D, van Noort JM. Broad expression of Toll-like receptors in the human central nervous system. J Neuropathol Exp Neurol 2002; 61 (11): 1013-1021. [ Links ]

    10. Akira S. TLR signaling. Curr Top Microbiol Immunol 2006; 311: 1-16. [ Links ]

    11. Mariathasan S, Monack DM. Inflammasome adaptors and sensors: intracellular regulators of infection and inflammation. Nat Rev Immunol 2007; 7 (1): 31-40. [ Links ]

    12. Martinon F, Hofmann K, Tschopp J. The pyrin domain: a possiblemember of the death domain-fold family implicated in apoptosis and inflammation. Current Biology 2001; 11 (4): R118-R120. [ Links ]

    13. Srinivasula SM, Poyet JL, Razmara M, Datta P, Zhang Z, Alnemri ES. The PYRIN-CARD protein ASC is an activating adaptor for caspase-1. J Biol Chem 2002; 277 (24): 21119-21122. [ Links ]

    14. Thornberry NA, Bull HG, Calaycay JR, Chapman KT, Howard AD, Kostura MJ et al. A novel heterodimeric cysteine protease is required for interleukin-1 processing in monocytes. Nature 1992; 356 (6372): 768-774. [ Links ]

    15. Schaeffler A, Gross P, Buettner R, Bollheimer C, Buechler C, Neumeier M et al. Fatty acidinduced induction of Toll-like receptor-4/nuclear factor-kappaB pathway in adipocytes links nutritional signalling with innate immunity. Immunology 2009; 126 (2): 233-245. [ Links ]

    16. Kim SJ, Choi Y, Choi YH, Park T. Obesity activates toll-like receptor-mediated proinflammatory signaling cascades in the adipose tissue of mice. J Nutr Biochem 2012; 23 (2): 113-122. [ Links ]

    17. Vitseva OI, Tanriverdi K, Tchkonia TT, Kirkland JL, McDonnell ME, Apovian CM, et al. Inducible Toll-like receptor and NF-kappaB regulatory pathway expression in human adipose tissue. Obesity 2008; 16 (5): 932-937. [ Links ]

    18. Milanski M, Degasperi G, Coope A, Morari J, Denis R, Cintra DE et al. Saturated fatty acids produce an inflammatory response predominantly through the activation of TLR4 signaling in hypothalamus: implications for the pathogenesis of obesity. J Neurosci 2009; 29 (2): 359-370. [ Links ]

    19. Vandanmagsar B, Youm YH, Ravussin A, Galgani JE, Stadler K, Mynatt RL et al. The NLRP3 inflammasome instigates obesity-induced inflammation and insulin resistance. Nat Med 2011; 17 (2): 179-188. [ Links ]

    20. Betanzos-Cabrera G, Guerrero-Solano JA, Martínez-Pérez MM, Calderón-Ramos ZG, Belefant-Miller H, Cancino-Diaz JC. Pomegranate juice increases levels of paraoxonase1 (PON1) expression and enzymatic activity in streptozotocin-induced diabetic mice fed with a highfat diet. Food Res Inter 2011; 44 (5): 1381-1385. [ Links ]

    21. González-Benitez JF, Juarez-Verdayes MA, Rodriguez-Martinez S, Cancino-Diaz ME, Garcia-Vazquez F, Cancino-Diaz JC. The NALP3/Cryopyrin-inflammasome complex is expressed in LPS-induced ocular inflammation. Mediators inflamm 2008; 2008: 614345. [ Links ]

    22. Caricilli AM, Nascimento PH, Pauli JR, Tsukumo DM, Velloso LA, Carvalheira JB et al. Inhibition of toll-like receptor 2 expression improves insulin sensitivity and signaling in muscle and white adipose tissue of mice fed a highfat diet. J Endocrinol 2008; 199 (3): 399-3406. [ Links ]

    23. Kuo LH, Tsai PJ, Jiang MJ, Chuang YL, Yu L, Lai KT et al. Toll-like receptor 2 deficiency improves insulin sensitivity and hepatic insulin signalling in the mouse. Diabetologia 2011; 54(1): 168-179. [ Links ]

    24. Davis JE, Braucher DR, Walker-Daniels J, Spurlock ME. Absence of Tlr2 protects against highfat diet induced inflammation and results in greater insulinstimulated glucose transport in cultured adipocytes. J Nutr Biochem 2011; 22 (2): 136-141. [ Links ]

    25. Poulain-Godefroy O, Le Bacquer O, Plancq P, Lecoeur C, Pattou F, Frühbeck G et al. Inflammatory role of Toll-like receptors in human and murine adipose tissue. Mediators Inflamm 2010; 2010: 823486. [ Links ]

    26. Kim S, Jin Y, Choi Y, Park T. Resveratrol exerts anti-obesity effects via mechanisms involving down-regulation of adipogenic and inflammatory processes in mice. Biochem Pharmacol 2011; 81 (11): 1343-1351. [ Links ]

    27. Hsueh HW, Zhou Z, Whelan J, Allen KG, Moustaid-Moussa N, Kim H et al. Stearidonic and Eicosapentaenoic Acids Inhibit Interleukin-6 Expression in ob/ob Mouse Adipose Stem Cells via Toll-Like Receptor-2-Mediated Pathways. J Nutr 2011; 141 (7): 1260-1266. [ Links ]

    28. Himes RW, Smith CW. Tlr2 is critical for diet-induced metabolic syndrome in a murine model. FASEB J 2010; 24 (3): 731-739. [ Links ]

    29. Kopp A, Buechler C, Neumeier M, Weigert J, Aslanidis C, Schölmerich J et al. Innate immunity and adipocyte function: ligand-specific activation of multiple Toll-like receptors modulates cytokine, adipokine, and chemokine secretion in adipocytes. Obesity 2009; 17 (4): 648-656. [ Links ]

    30. Vijay-Kumar M, Aitken JD, Carvalho FA, Cullender TC, Mwangi S, Srinivasan S et al. Metabolic syndrome and altered gut microbiota in mice lacking Toll-like receptor 5. Science 2010; 328 (2975): 228-231. [ Links ]

    31. Xu H, Barnes GT, Yang Q, Tan G, Yang D, Chou CJ, et al. Chronic inflammation in fat plays a crucial role in the development of obesity-related insulin resistance. J Clin Invest 2003; 112 (12): 1821-1830. [ Links ]

    32. Murano I, Barbatelli G, Parisani V, Latini C, Muzzonigro G, Castellucci M, et al. Dead adipocytes, detected as crownlike structures, are prevalent in visceral fat depots of genetically obese mice. J Lipid Res 2008; 49 (7): 1562-1568. [ Links ]

    33. Weisberg SP, McCann D, Desai M, Rosenbaum M, Leibel RL, Ferrante AW Jr. Obesity is associated with macrophage accumulation in adipose tissue. J Clin Invest 2003; 112 (12): 1796-1808. [ Links ]

    34. Cancello R, Henegar C, Viguerie N, Taleb S, Poitou C, Rouault C et al. Reduction of macrophage infiltration and chemoattractant gene expression changes in white adipose tissue of morbidly obese subjects after surgery-induced weight loss. Diabetes 2005; 54 (8): 2277-2286. [ Links ]

    35. Scholtes VP, Versteeg D, de Vries JP, Hoefer IE, Schoneveld AH, Stella PR et al. Toll-like receptor 2 and 4 stimulation elicits an enhanced inflammatory response in human obese patients with atherosclerosis. Clin Sci (Lond) 2011; 121 (5): 205-214. [ Links ]

    36. Jermendy A, Korner A, Kovacs M, Kaszas E, Balázsovics J, Szocs A et al. Association between toll-like receptor polymorphisms and serum levels of tumor necrosis factor-alpha and its soluble receptors in obese children. Med Sci Monit 2010; 16 (4):CR180-185. [ Links ]

    37. Apovian CM, Bigornia S, Mott M, Meyers MR, Ulloor J, Gagua M et al. Adipose macrophage infiltration is associated with insulin resistance and vascular endothelial dysfunction in obese subjects. Arterioscler Thromb Vasc Biol 2008; 28 (9): 1654-1659. [ Links ]