Fig. 3. Family genealogical tree, in 1999. 
The arrow indicates the patient index. +: Patient carrier of the W421X mutation ; -: Patient non-carrier of the W421X mutation.
Abbreviations: FAP: Familial Adenomatous Polyposis ; Ca?: Possible cancer; CCR: Colorectal cancer; N C : Colonoscopy not accepted;
C N: colonoscopy reported as normal; CM: Breast cancer; C Pr: Prostate cancer; ¿: No clinical information available.