ALVAREZ-MUGICA, M. et al. Use of zoledromic acid on pain control in stages M1b of prostate cancer. []. , 31, 10, pp.1100-1106. ISSN 0210-4806.

Objectives: To probe the use of Zoledromic acid in the control of the pain due to bone methastasis of a prostate cancer. Material and method: We included in our study 37 consecutive patients diagnosed of prostate cancer who developed bone methastasis during 2005 and 2006 to whom we gave a 4 mg dose of Zoledromic acid during a mean time of 10.24 months. Results: We observed a complete control of the pain in 8 of the 20 patients, and partially in 6 of those patients. We did not evaluate any adverse reaction due to this treatment. Conclusions: We still yet to know whether the administration of this treatment in the early stages of the prostate cancer could prevent or retard the appearance of bone methastasis.

: Zoledromic acid; Bone methastasis; Bone pain.

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