33 3 
Home Page  

  • SciELO

  • Google
  • SciELO
  • Google


Nefrología (Madrid)

 ISSN 1989-2284 ISSN 0211-6995

SANTOS, Clara et al. An unusual cause of glomerular hematuria and acute kidney injury in a chronic kidney disease patient during warfarin therapy. []. , 33, 3, pp.400-403. ISSN 1989-2284.  https://dx.doi.org/10.3265/Nefrologia.pre2012.Oct.11617.

^len^aWarfarin is a well-established cause of gross hematuria. However, impaired kidney function does not occur except in the rare instance of severe blood loss or clot formation that obstructs the urinary tract. It has been recently described an entity called warfarin-related nephropathy, in which acute kidney injury is caused by glomerular hemorrhage and renal tubular obstruction by red blood cell casts. We report a patient under warfarin treatment with chronic kidney disease, macroscopic hematuria and acute kidney injury. A renal biopsy showed massive occlusion of renal tubules by red blood cells and casts. The possible relationship of the warfarin therapy, intratubular hemorrhage and acute kidney injury is discussed.^les^aLa warfarina es una causa muy conocida de hematuria macroscópica. Sin embargo, el deterioro de la función renal no ocurre salvo en el caso inusual de gran pérdida de sangre o formación de coágulos que obstruyen el tracto urinario. Recientemente se ha descrito una entidad denominada nefropatía relacionada con la warfarina en la que el fracaso renal agudo es provocado por hemorragia glomerular y obstrucción tubular renal por cilindros de glóbulos rojos. Exponemos el caso de un paciente bajo tratamiento de warfarina con enfermedad renal crónica, hematuria macroscópica e insuficiencia renal aguda. Una biopsia renal mostró una oclusión masiva de túbulos renales por cilindros de glóbulos rojos. Debatimos la posible relación de la terapia con warfarina, la hemorragia intratubular y el fracaso renal agudo.

: .

        · | |     · |     · ( pdf )

 

Creative Commons License All the contents of this journal, except where otherwise noted, is licensed under a Creative Commons Attribution License