RODRIGUEZ-RODRIGUEZ, E.; BERMEJO, L. M.; LOPEZ-SOBALER, A. M.    ORTEGA, R. M.. An inadequate intake of manganese may favour insulin resistance in girls. []. , 26, 5, pp.965-970. ISSN 1699-5198.

Aim: to study the relationship between an adequate manganese (Mn) intake and glucose, insulin levels and insulin resistance among healthy children from Madrid (Spain). Materials and methods: 573 schoolchildren between 8 and 13 years old were studied. Energy and nutrients intake (especially Mn) was calculated with a "3-day diet record". Mn intake was compared to Adequate Intakes (AI) for this mineral. Weight and height were measured and body mass index (BMI) calculated. Fasting glucose and insulin were determined and the HOMA index was calculated to establish the presence of insulin resistance in children. Results: Girls with and inadequate intake (below the 100% of the AI value) had higher insulin and HOMA values than girls with adequate AI values (equal or higher to 100% of AI). Having in mind confounding factors (energy, carbohydrates and lipids intake, BMI and age), a significant positive correlation was found between the contribution of Mn intake to AI and HOMA levels in girls. Conclusion: It seems important to ensure an adequate Mn intake in girls in order to prevent insulin resistance and diabetes type 2 in the future.

: Manganese; Adequate intake; Insulin resistance; Schoolchildren.

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