SAMBRA VASQUEZ, Verónica; TAPIA FERNANDEZ, Carolina    VEGA SOTO, Claudia. Effect of fragmentation and quality of carbohydrates diet on metabolic control parameters in insulin treated type 2 diabetic individuals. []. , 31, 4, pp.1566-1573. ISSN 1699-5198.  https://dx.doi.org/10.3305/nh.2015.31.4.8359.

Introduction: Currently there is no consensus regarding fragmentation, quantity and quality of carbohydrates (CHO) that should be followed by insulin treated type 2 diabetic individuals (ITT2D). Objective: To determine the relationship between the meal times, quality of available CHO in every meal and the metabolic control parameters in ITT2D individuals with a single or double dose of intermediate-acting insulin. Methods: 40 ITT2D individuals were evaluated, using food surveys to obtain the quantity of CHO, glycemic index (GI), glycemic load (GL) in every meal and meal times. The metabolic control was determined through lab exams (glycated hemoglobin; HbA1c, venous fasting glycaemia) and fasting (FBG), preprandial (PreG), postprandial (PostG) and bed time (BTG) capilar glycaemia using a glucometer. Statistical analysis were applied considering significant as p<0,05. Results: Individuals recorded an average of 4,9 ± 1,1 meals a day. It was found an asociation between lunch GL and PostG (r=0,317; p<0,05) and BTG (r=0,321; p<0,05). BTG was inversely correlated with the mealsf distribution (r = -0,346; p<0,05) and there was a trend to show lower values of BTG with individuals conducting ≥ 5 meals per day. It was observed that FBG predicts a 65% the variability of HbA1c (r =0,805; r² =0,648; p<0,001). Conclusion: The meal times in ITT2D individuals with s single or double dose of intermediate-acting insulin could improve BTG.

: Meal times; Glycemic Index; Dietary carbohydrates; Diabetes Mellitus; Type 2; Hemoglobin A; Glycosylated.

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