LUIS, Daniel Antonio de; IZAOLA, Olatz; BACHILLER, Pablo    PEREZ CASTRILLON, José. Effect on quality of life and handgrip strength by dynamometry of an enteral specific suplements with beta-hydroxy-beta-methylbutyrate and vitamin D in elderly patients. []. , 32, 1, pp.202-207. ISSN 1699-5198.  https://dx.doi.org/10.3305/nh.2015.32.1.9083.

Aim: the aim of our study was to investigate the effect on strenght and quality of life of an enhanced specific enteral formula with HMBD and vitamin D in elderly patients. Methods: we conducted an open-label study. General assessment of nutritional status included measurements of body weight, height, body mass index (kg/m²) and bioimpedance. Handgrrip strength was measured by dynamometry. QOL (quality of life) was assessed using the well validated SF 36 questonnaire. Albumin, prealbumin, transferrin and 25-OH vitamin D were measured. All these parameters were recorded at basal time and after 12 weeks of nutritional intervention. Results: patients were divided in two groups by the median percentage of weight improvement (3.4%); group 1 (percentage of weight improvement <3.4%) and group 2 (percentage of weight improvement >3.4%). In group 1, patients showed an improvement in prealbumin and vitamin D levels. In group 2, patients showed an improvement of BMI, weight, fat mass, fat free mass, prealbumin, vitamin D levels, role physical domain of SF 36 , general health domain of SF 36 and handgrip strength. The volumetric consumption rates of the formula were higher in group 2 than group 1 (group 1: 1.25 + 0.78 units/day [1.81 +/-0.9 g per day of HMBD) vs. group 2: 1.86 + 0.82 units/day (2.79 +/-1.1 g per day of HMBD]). Conclusions: elderly patients with a previous weight loss and with a high consumption of a HMBD and vit D enhanced formula had a significant improvement in anthropometric, biochemical parameters, handgrip strength and quality of life.

: Elderly; Handgrip strenght; HMBD; Vitamin D; Quality of life.

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