HIGUERA-PULGAR, Isabel et al. Dietary intake and nutritional status in oncology patients who start treatment with tyrosine kinase inhibitors. []. , 32, 3, pp.1200-1207. ISSN 1699-5198.  https://dx.doi.org/10.3305/nh.2015.32.3.9315.

Background: in recent years, researching about new oral antineoplastics has progressed while its impact on dietary intake and nutritional status (NS) hasnft developed enough yet. Objectives: dietary intake and NS assessment in patients who start treatment with tyrosine kinase inhibitors (TKI) and evaluate its impact on them. Methods: an observational, prospective-six-months study, in which were included patients starting treatment with TKI. The intake was evaluated by a 24 h dietary record and a food frequency questionnaire. The NS was evaluated by anthropometric measurements and the patient-generated Global Subjective Assessment (PG-GSA); the results were compared with the Spanish references (SENC-semFYC, 2007 and O. Moreiras, 2013). Friedman test, χ2, Wilcoxon, Kruskal-Wallis and Mann-Whitney were used in the statistical analysis. Significance p<0.05. Results: 22 patients (54.5% male) were included. At baseline, NS was adequate in 73.9% of patients according PG-GSA. Weight loss was no significant, although a high percentage of the energy and protein requirements hadnLt been reached. The caloric intake was positively related with the number of meals. Dietary habits did not change during treatment. Conclusion: dietary intake did not reach nutritional requirements at baseline. The TKI donLt seem to affect the patientLs intake and nutritional status. The research about these parameters before starting treatment could prevent future complications and it would guide the dietary advice.

: Dietary intake; Nutrition status; Dietary patterns; Antineoplastic agent.

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