LIU, Changwei et al. Correlation of serum vitamin D level with type 1 diabetes mellitus in children: a meta-analysis. []. , 32, 4, pp.1591-1594. ISSN 1699-5198.  https://dx.doi.org/10.3305/nh.2015.32.4.9198.

Objective: to assess the relationship between serums vitamin D level and type 1 diabetes mellitus (T1DM) in children. Methods: the following electronic databases were searched until Sep 2014 to identify relevant studies that assessed the relationship between serum vitamin D with T1DM: PubMed\EMbase\Medline\Central Register of Controlled Trials\CBM\Chinese National Knowledge Infrastructure (CNKI)\wangfang; The NOS scale was used to evaluate the quality of studies, and the statistical tests were performed by Stata 11.0 software. Result: a total of 10 studies were included in this study. Our results showed that serum vitamin D was significantly lower in children with T1DM than in healthy controls (MD = -0.60, P < 0.05). No evidence support publication bias in present study. Conclusion: the meta-analysis suggests that serum vitamin D level is associated with T1DM in children.

: Serum vitamin D; T1DM; Meta-analysis.

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