Nutrición Hospitalaria
ISSN 1699-5198 ISSN 0212-1611
CALMARZA, Pilar et al. Vitamin D levels in patients with recent cancer diagnosis. []. , 35, 4, pp.903-908. 18--2019. ISSN 1699-5198. https://dx.doi.org/10.20960/nh.1675.
Introduction:
apart from the known effects of vitamin D on phospho-calcium homeostasis, in recent years there is great interest in its extra-bone effects.
Objectives:
to know the concentration of 25-hydroxyvitamin D (25[OH] D) in newly diagnosed patients of cancer and to verify if there are differences between the different types of cancer.
Material and methods:
cross-sectional study of a cohort of recent diagnosed cancer patients who were referred to Endocrinology consultation for a nutritional pre-surgery evaluation. One hundred and thirty-nine medical histories were reviewed. The socio-demographic and biometric data and 25(OH) D concentration were collected.
Results:
seventy-one of 139 patients had urological cancer, 27 had colorectal cancer (CRC), 35 had head and neck cancer and six, other types of cancer. The mean concentration of 25(OH) D was 50.41 nmol/l (95% CI = 46.67-54.14); 57.97% of patients showed vitamin D deficiency (< 50 nmol/l) and 21.74%, insufficiency (50-75 nmol/l). We found a statistically significant higher prevalence of deficiency (p < 0.01) in head and neck cancer compared to urological cancer: 68.57% and 49.29%, respectively. Year season significantly modifies 25(OH) D concentration (p < 0.01).
Conclusions:
there is a high prevalence of vitamin D deficiency among recent diagnosed cancer patients (especially in CRC and head and neck cancer). The use of reference values adjusted by year season could improve the study of 25(OH) D concentrations.
: Vitamin D; Deficiency; Urological cancer; Recently diagnosed; Obesity; Head and neck cancer.