Nutrición Hospitalaria
ISSN 1699-5198 ISSN 0212-1611
FORNASINI, Marco et al. Efficacy of a Lupinus mutabilis Sweet snack as complement to conventional type 2 diabetes mellitus treatment. []. , 36, 4, pp.905-911. 17--2020. ISSN 1699-5198. https://dx.doi.org/10.20960/nh.02590.
Introduction:
therapeutic lifestyles changes including frequent consumption of legumes have resulted in improved metabolic control and decreased blood pressure in type 2 diabetes-mellitus (T2DM) patients.
Objective:
this was a quasi-experimental-28-week crossover-study that assessed the effect of daily consumption of the legume Lupinus mutabilis (LM) on metabolic control of T2DM patients under hypoglycemic oral treatment.
Material and methods:
we recruited 79 adult male and female patients that were followed for 14-weeks without LM consumption and then received increasing doses of a LM-based-snack for other 14-weeks.
Results:
there was a significant decrease in blood pressure and a significant increase in HDL-cholesterol by the end of the study period. While patients with A1C concentrations > 8 and ≤ 10 did not significantly improve their metabolic control, patients with serum A1C concentrations ≤ 8.0% reduced significantly their A1C after the intervention and 71% achieved a target concentration of 6.5%.
Conclusion:
patients with T2DM could benefit with the addition of LM-snack to their conventional treatment.
: Type 2 diabetes mellitus; Glycated hemoglobin; Lupinus; Humans.