Nutrición Hospitalaria
ISSN 1699-5198 ISSN 0212-1611
RODRIGUEZ-VIDALES, Edgar P et al. Severe COVID-19 patients have severe vitamin D deficiency in Northeast Mexico. []. , 39, 2, pp.393-397. 09--2022. ISSN 1699-5198. https://dx.doi.org/10.20960/nh.03731.
Objective:
the association between vitamin D and COVID-19 severity is not consistent. We compared prevalences and analyzed the association between vitamin D deficiency and COVID-19 severity in Northeast Mexico.
Methods:
this was a cross-sectional study with individuals consecutively included at a referral diagnostic center during March-September 2020 (n = 181). Concurrently, every patient admitted to intensive care was also consecutively included (n = 116). Serum 25(OH)D < 20 ng/mL was considered vitamin D deficiency. Descriptive, ANOVA, and multivariate ordinal regression analyses were performed.
Results:
vitamin D deficiency prevalence was 63.8 % (95 % CI, 54.7, 72.0) in severe COVID-19; 25.6 % (95 % CI, 17.4, 36.0) in mild COVID-19; and 42.4 % (95 % CI, 33.2, 52.3) in non-diseased individuals. Vitamin D deficiency increased 5 times the odds of severe COVID-19 (95 % CI, 1.1, 24.3), independently of sex, age, body mass index, and inflammatory markers.
Conclusions:
this study is the first report of vitamin D deficiency in Northeast Mexico. Vitamin D deficiency was associated with COVID-19 severity.
: Vitamin D deficiency; SARS-CoV-2; Laboratory parameters; COVID-19; Serum 25(OH)D.