BARREIRO GARCIA, G. et al. Acute adrenal insuficiency caused by adrenal hemorrhage as a first manifestation of the antiphospholipid syndrome: A case report and review . []. , 19, 1, pp.19-22. ISSN 0212-7199.

Although adrenal hemorrhage is an unusual feature of antiphospholipid syndrome (APS), it can be its first clinical manifestation. The pathogenetic substratum is the thrombosis of the adrenal veins leading to hemorrhagic infarction. Recurrences are frequent in patients with APS-related thrombosis, thus long-term anticoagulation is advocated by most authors. 

: Adrenal hemorrhage; Systemic lupus erythematosus; Antiphospholipid syndrome; Anticoagulant therapy.

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