ALVAREZ-LOPEZ, L. C. et al. Conscious analgo-sedation with midazolam and fentanyl (OTFC) in children. []. , 13, 6, pp.406-409. ISSN 1134-8046.

Multiple bone marrow aspirations and lumbar punctures are performed on children with leukaemia and other neo-plastic disorders during the course of their illnesses. These procedures may give rise to considerable pain and distress in children. Fentanyl, a short-acting potent synthetic opioid, can produce sedation through oral transmucosal (Oral Transmucosal Fentanyl Citrate -OTFC-) administration. The combination of OTFC and oral midazolam was a useful conscious sedation technique for painful procedures, such as lumbar punctures and bone marrow aspirations in this patients.

: Opioid drugs; cancer pain; fentanyl; sedation; children.

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