AMEZCUA-HERNANDEZ, V.    GALVEZ-MONTOSA, F.. Are immediate-release opioids useful for phantom limb pain? Clinical case. []. , 24, 5, pp.269-272. ISSN 1134-8046.  https://dx.doi.org/10.20986/resed.2017.3579/2017.

When a limb amputation is performed, neuropathic pain may occur in 80 % of patients. The therapeutic approach of this pain, is a complex aspect. Usually, coadjuvant neuromodulator are used to control pain in a complementary way to opiates (gabapentin, bupivacaine, pregabalin), but in many cases these measures are not effective.

Neuropathic breakthrough pain crises are described and, because of the half-life and pharmacokinetic behavior of neuromodulatory drugs, pain control is not achieved.

In our experience, the use of fast-release opioids in the intranasal-peptine presentation in crisis of breakthrough neuropathic pain led to its disappearance or the reduction to tolerable levels.

: Oncological Pain; breakthrough neuropathic pain; intranasal fentanil peptine.

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