Revista de la OFIL
ISSN 1699-714X ISSN 1131-9429
VARELA-REY, I et al. Galenic aspects of submucosal injection solutions for use in endoscopic polypectomy. []. , 30, 2, pp.131-139. 15--2021. ISSN 1699-714X. https://dx.doi.org/10.4321/s1699-714x2020000200013.
Endoscopic submucosal dissection (ESD) and endoscopic mucosal resection (EMR) are the main techniques used in the removal of intestinal polyps. In both techniques a submucosal solution is injected to create a hub under the lesion that separates the mucosa from the muscular layer itself. This allows a better delimitation of the lesion and facilitates its resection.
In clinical practice, many solutions have been tested for this use, being used in most cases out off-label and without galenic, physicochemical or microbiological control, despite being parenteral administration solutions.
The objective of this study is to carry out a review of the main solutions used, as well as their limitations and the main advances made in this area.
: Submucosa; injection solution; polypectomy; endoscopic.