Abstract

MOYANO CALVO, J.L. et al. Age's influence in superficial bladder cancer's behaviour. Actas Urol Esp [online]. 2005, vol.29, n.1, pp.82-88. ISSN 0210-4806.

Introduction: Transitional bladder cancer is infrequent in younger people. The tumor's agresiveness in this poulation is subject of discussion.. We present our experience. Material & method: 551primary tumors, with at least one year of follow-up. Group A (less than 41 years old), Group B (bigger than 40 years old). We compare, stage, grade, lymphatic permeation, multiplicity, recurrence, progression, sex, T.L.E. (time free of disease), volume. We do uni and multivariate analysis. Results: 17 tumors in youngers than 41 years (2,1%). The recurrence rate is 11,8% in Group A and 36% in Group B (p .041). Progresión rate: 0% in A and 4,1% in B (p .253). In Group A, T1 tumors T1 (13,3% vs. 39%), G2 tumors (0% vs. 36,7%); withoutsin lymphatic permeation (0% vs a 35%) and solitary tumors (13,3% vs. 35,3%) have statistically less recurrence. In univariate analysis we apreciate statitsticaly differences in relation with grade (p .002) and sex (p .011). In multivariate analysis, stage, "group of age" and prophylactic treatment are independent variables for recurrence, and grade for progression. Conclusions: In youngers than 41 years old: - Less patologic agressivity (0% G3) - Group of age is independent prognostic variable for recurrence, but not pfor progression, despite a "less agressive behaviour":         - 11,8% recurrence         - 0% progression - T.L.E. bigger (one year more) - Higher incidence in women (41% vs. 11%) - Less recurrence in T1 tumors (13,3% vs. 39%), G2 tumors (0% vs 36,7%) and solitary tumors (13,3% vs 35,32%).

Keywords : Bladder cancer; Prognostic factors; Age.

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