Abstract

EBEL SEPULVEDA, Luis et al. Vanishing prostate cancer: Clinical presentation and histological review. Actas Urol Esp [online]. 2009, vol.33, n.9, pp.956-959. ISSN 0210-4806.

The impossibility to identify cancer in the final surgical specimen has been reported in some patients with prostate cancer undergoing radical prostatectomy. This has been attributed to either a wrong diagnosis or pathological technique, or to spontaneous or biopsy-induced cure of the tumor. This study assessed the incidence of vanishing prostate cancer in our department for 12 years, the clinical characteristics of patients, and their follow-up. The initial puncture biopsies were also re-evaluated using inmunohistochemical stains. Prostate cancer could not be confirmed in the surgical specimen in six out of 346 operated patients (1.73%) receiving no neoadjuvant therapy. When the initial biopsies were reviewed, cancer was only confirmed in three patients. Incidence of vanishing cancer at our department in the 12-year period considered was 0.86% (3/346). No tumor relapse occurred during 4.5 years of follow-up.

Keywords : Prostate; Biopsy; Adenocarcinoma; Prostatectomy; Pathology.

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